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1

Synthesis of Orthogonally Protected Bis(aminomethyl)malonic Acid, and Its Use as a Key Building Block in the Preparation of Cyclic Peptide Conjugates of 2-N-Alkyl-1,2,3,4-tetrahydroisoquinoline on a Solid Support

Pasi Virta, Jaana Rosenberg, Tuomas Karskela, Petri Heinonen, Harri Lönnberg

Journal:

European Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 297 KB

english, 2001

2

Thio Effects on the Departure of the 3′-Linked Ribonucleoside from Diribonucleoside 3′,3′-Phosphorodithioate Diesters and Triribonucleoside 3′,3′,5′-Phosphoromonothioate Triesters: Implications for Ribozyme Catalysis

Tuomas Lönnberg, Mikko Ora, Sami Virtanen, Harri Lönnberg

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

3

Oxidation of an Oligonucleotide-Bound CeIII/Multiphosphonate Complex for Site-Selective DNA Scission

Tuomas Lönnberg, Yuichiro Aiba, Yuya Hamano, Yoshitaka Miyajima, Jun Sumaoka, Makoto Komiyama

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 458 KB

english, 2010

4

Understanding Catalysis of Phosphate-Transfer Reactions by the Large Ribozymes

Dr. Tuomas Lönnberg

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 2.02 MB

english, 2011

5

ChemInform Abstract: Hydrolytic Reactions of Nucleoside Phosphoramidates: Kinetics and Mechanisms

Tuomas Lonnberg, Mikko Ora, Harri Lonnberg

Journal:

Year:

2010

File:

PDF, 15 KB

2010

6

Solid-Supported Synthesis of Bicyclic Peptides Containing Three Parallel Peptide Chains

Tuomas Karskela, Petri Heinonen, Pasi Virta, Harri Lönnberg

Journal:

European Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 122 KB

english, 2003

7

Chemical models for ribozyme action

Tuomas Lönnberg, Harri Lönnberg

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 398 KB

english, 2005

8

Manipulation of Single-Stranded DNA by Using an Artificial Site-Selective DNA Cutter Composed of Cerium(IV)/EDTA and Phosphonate–Oligonucleotide Conjugates

Dr. Yuichiro Aiba, Dr. Tuomas Lönnberg, Prof. Dr. Makoto Komiyama

Journal:

Chemistry – An Asian Journal

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

9

Prompt site-selective DNA hydrolysis by Ce(iv)–EDTA using oligonucleotide multiphosphonate conjugates

Lönnberg, Tuomas, Suzuki, Yuta, Komiyama, Makoto

Journal:

Organic & Biomolecular Chemistry

Year:

2008

Language:

english

File:

PDF, 456 KB

english, 2008

10

Mimics of small ribozymes utilizing a supramolecular scaffold

Lönnberg, Tuomas A., Helkearo, Mia, Jancsó, Attila, Gajda, Tamás

Journal:

Dalton Transactions

Year:

2012

Language:

english

File:

PDF, 752 KB

english, 2012

11

Intracomplex general acid/base catalyzed cleavage of RNA phosphodiester bonds: the leaving group effect

Lönnberg, Tuomas, Luomala, Mikko

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 214 KB

english, 2012

12

Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5′-monophosphates bearing a biodegradable protecting group

Leisvuori, Anna, Aiba, Yuichiro, Lönnberg, Tuomas, Poijärvi-Virta, Päivi, Blatt, Laurence, Beigelman, Leo, Lönnberg, Harri

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 490 KB

english, 2010

13

2,6-Bis(functionalized) purines as metal-ion-binding surrogate nucleobases that enhance hybridization with unmodified 2′-O-methyl oligoribonucleotides

Taherpour, Sharmin, Lönnberg, Harri, Lönnberg, Tuomas

Journal:

Organic & Biomolecular Chemistry

Year:

2013

Language:

english

File:

PDF, 451 KB

english, 2013

14

Can Phosphate-Branched RNA Persist under Physiological Conditions?

Lönnberg, Tuomas A.

Journal:

Year:

2012

Language:

english

File:

PDF, 606 KB

english, 2012

15

Interaction of Pd2+ complexes of 2,6-disubstituted pyridines with nucleoside 5′-monophosphates

Golubev, Oleg, Lönnberg, Tuomas, Lönnberg, Harri

Journal:

Journal of Inorganic Biochemistry

Year:

2014

Language:

english

File:

PDF, 793 KB

english, 2014

16

Metal-Ion-Binding Analogs of Ribonucleosides: Preparation and Formation of Ternary Pd 2+ and Hg 2+ Complexes with Natural Pyrimidine Nucleosides

Golubev, Oleg, Lönnberg, Tuomas, Lönnberg, Harri

Journal:

Helvetica Chimica Acta

Year:

2013

Language:

english

File:

PDF, 422 KB

english, 2013

17

Hydrolytic Reactions of Guanosyl-(3‘,3‘)-uridine and Guanosyl-(3‘,3‘)-(2‘,5‘-di- O -methyluridine)

Kiviniemi, Anu, Lönnberg, Tuomas, Ora, Mikko

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 112 KB

english, 2004

18

Hydrolysis of 2‘,3‘- O -methyleneadenos-5‘-yl Bis(2‘,5‘-di- O -methylurid-3‘-yl) Phosphate, a Sugar O -Alkylated Trinucleoside 3‘,3‘,5‘-Monophosphate: Implications for the Mechanism of Large Ribozymes

Lönnberg, Tuomas, Mikkola, Satu

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 179 KB

english, 2004

19

Metal-Ion-Mediated Base Pairing between Natural Nucleobases and Bidentate 3,5-Dimethylpyrazolyl-Substituted Purine Ligands

Taherpour, Sharmin, Golubev, Oleg, Lönnberg, Tuomas

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 735 KB

english, 2014

20

Hydrolytic Reactions of Diribonucleoside 3‘,5‘-(3‘- N -Phosphoramidates): Kinetics and Mechanisms for the P−O and P−N Bond Cleavage of 3‘-Amino-3‘-deoxyuridylyl-3‘,5‘-uridine

Ora, Mikko, Mattila, Kati, Lönnberg, Tuomas, Oivanen, Mikko, Lönnberg, Harri

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

21

Hydrolysis of 2',3'- O -Methyleneadenosin-5'-yl Bis-5'- O -Methyluridin-3'-yl Phosphate: The 2'-Hydroxy Group Stabilizes the Phosphorane Intermediate, Not the Departing 3'-Oxyanion, by Hydrogen Bonding

Lönnberg, Tuomas, Korhonen, Jonna

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

22

An Orthogonally Protected α , α -Bis(aminomethyl)- β - alanine Building Block for the Construction of Glycoconjugates on a Solid Support

Katajisto, Johanna, Karskela, Tuomas, Heinonen, Petri, Lönnberg, Harri

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 130 KB

english, 2002

23

The Zn 2+ Complex of 1,4,7,10-Tetraazacyclododecane as an Artificial Nucleobase

Laine, Maarit, Aromaa, Maria, Virta, Pasi, Lönnberg, Tuomas, Poijärvi-Virta, Päivi, Lönnberg, Harri

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 219 KB

english, 2011

24

Hydrolytic Stability of a Phosphate-Branched Oligonucleotide Incorporating a Ribonucleoside 3′-Phosphotriester Unit

Lönnberg, Tuomas

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2006

Language:

english

File:

PDF, 428 KB

english, 2006

25

Kinetics and Mechanisms for the Isomerization of Internucleosidic 3'-O-P-CH2-5' and 3'-O-P-CH(OH)-5' Linkages to Their 2',5'-Counterparts

Lönnberg, Tuomas, Králíková, Šárka, Rosenberg, Ivan, Lönnberg, Harri

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

26

Participation of an additional 4′-hydroxymethyl group in the cleavage and isomerization of ribonucleoside 3′-phosphodiesters

Lain, Luigi, Lönnberg, Harri, Lönnberg, Tuomas

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 299 KB

english, 2015

27

Fluorescence probing of metal-ion-mediated hybridization of oligonucleotides

Taherpour, Sharmin, Lönnberg, Tuomas

Journal:

Year:

2015

Language:

english

File:

PDF, 782 KB

english, 2015

28

Synthesis of 7-substituted 3-β-D-ribofuranosyl-3H-imidazo[2,1-i]purines

Karskela, Tuomas, Klika, Karel D., Lönnberg, Harri

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

29

Synthesis of Bicyclic Peptides

Karskela, Tuomas, Virta, Pasi, Lonnberg, Harri

Journal:

Current Organic Synthesis

Year:

2006

Language:

english

File:

PDF, 166 KB

english, 2006

30

Pd2+-mediated base pairing in oligonucleotides

Golubev, Oleg, Turc, Guillaume, Lönnberg, Tuomas

Journal:

Journal of Inorganic Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

31

Cleavage of short oligoribonucleotides by a Zn2+ binding multi-nucleating azacrown conjugate

Laine, Maarit, Lönnberg, Tuomas, Helkearo, Mia, Lönnberg, Harri

Journal:

Inorganica Chimica Acta

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

32

On the feasibility of recognition of nucleic acid sequences by metal-ion-carrying oligonucleotides

Taherpour, Sharmin, Golubev, Oleg, Lönnberg, Tuomas

Journal:

Inorganica Chimica Acta

Year:

2016

Language:

english

File:

PDF, 546 KB

english, 2016

33

Selective Alkylation of C-Rich Bulge Motifs in Nucleic Acids by Quinone Methide Derivatives

Lönnberg, Tuomas, Hutchinson, Mark, Rokita, Steven

Journal:

Chemistry - A European Journal

Year:

2015

Language:

english

File:

PDF, 919 KB

english, 2015

34

5-Mercuricytosine: An Organometallic Janus Nucleobase

Ukale, Dattatraya, Shinde, Vaishali S., Lönnberg, Tuomas

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 623 KB

english, 2016

35

Intramolecular Participation of Amino Groups in the Cleavage and Isomerization of Ribonucleoside 3′-Phosphodiesters: The Role in Stabilization of the Phosphorane Intermediate

Lain, Luigi, Lönnberg, Harri, Lönnberg, Tuomas

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 539 KB

english, 2013

36

ChemInform Abstract: Thio Effects as a Tool for Mechanistic Studies of the Cleavage of RNA Phosphodiester Bonds: The Chemical Basis

Ora, Mikko, Lonnberg, Tuomas, Lonnberg, Harri

Journal:

Year:

2013

File:

PDF, 18 KB

2013

37

Metal-Dependent Nucleobase Recognition by Picolinamide

Dengale, Rohit A., Thopate, Shankar R., Lönnberg, Tuomas

Journal:

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

38

Fluorescent Oligonucleotide Probes for Screening High-Affinity Nucleobase Surrogates

Aro-Heinilä, Asmo, Lönnberg, Tuomas

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

39

Formation of Mixed-Ligand Complexes of Pd2+ with Nucleoside 5'-Monophosphates and Some Metal-Ion-Binding Nucleoside Surrogates

Golubev, Oleg, Lönnberg, Tuomas, Lönnberg, Harri

Journal:

Year:

2014

Language:

english

File:

PDF, 449 KB

english, 2014

40

Sulfurization of H-Phosphonate Diesters by Elemental Sulfur under Aqueous Conditions

Lönnberg, Tuomas

Journal:

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

41

Oligonucleotides Incorporating Palladacyclic Nucleobase Surrogates

Maity, Sajal Kumar, Lönnberg, Tuomas

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

42

Triplex Formation by Oligonucleotides Containing Organomercurated Base Moieties

Ukale, Dattatraya Uttam, Lönnberg, Tuomas

Journal:

Year:

2018

Language:

english

File:

PDF, 450 KB

english, 2018

43

Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside

Taherpour, Sharmin, Lönnberg, Tuomas

Journal:

Journal of Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 2.28 MB

english, 2012

44

2,6-Bis(1,4,7,10-tetraazacyclododecan-1-ylmethyl)pyridine and Its Benzene Analog as Nonmetallic Cleaving Agents of RNA Phosphodiester Linkages

Lain, Luigi, Lahdenpohja, Salla, Lönnberg, Harri, Lönnberg, Tuomas

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

45

Phosphodiester models for cleavage of nucleic acids

Mikkola, Satu, Lönnberg, Tuomas, Lönnberg, Harri

Journal:

Beilstein Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

46

Nucleic acids through condensation of nucleosides and phosphorous acid in the presence of sulfur

Lönnberg, Tuomas

Journal:

Beilstein Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 384 KB

english, 2016

47

2,6-Dimercuriphenol as a Bifacial Dinuclear Organometallic Nucleobase

Ukale, Dattatraya Uttam, Lönnberg, Tuomas

Journal:

Angewandte Chemie International Edition

Year:

2018

Language:

english

File:

PDF, 698 KB

english, 2018

48

2,6-Dimercuriphenol as a Bifacial Dinuclear Organometallic Nucleobase

Ukale, Dattatraya Uttam, Lönnberg, Tuomas

Journal:

Angewandte Chemie

Year:

2018

Language:

english

File:

PDF, 698 KB

english, 2018

49

Oligonucleotide–Palladacycle Conjugates as Splice-Correcting Agents

Hande, Madhuri, Saher, Osama, Lundin, Karin, Smith, C., Zain, Rula, Lönnberg, Tuomas

Journal:

Year:

2019

File:

PDF, 1.10 MB

2019

50

Synthesis and Hybridization Properties of Covalently Mercurated and Palladated Oligonucleotides

Ukale, Dattatraya, Maity, Sajal, Hande, Madhuri, Lönnberg, Tuomas

Journal:

Year:

2019

Language:

english

File:

PDF, 1.18 MB

english, 2019